Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780928 | 0.87 | THRB (0.37) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL9301192 | 0.84 | THRB (0.51) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL27766731 | 0.81 | HRH3 (0.43) | HRH3DRD3ALDH1A1KDM4ECDC25B | |
| SCHEMBL21312091 | 0.81 | ALDH1A1 (0.51) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL21312161 | 0.81 | ALDH1A1 (0.51) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL21312289 | 0.81 | ALDH1A1 (0.51) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL21312674 | 0.79 | HRH3 (0.55) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL27788181 | 0.78 | ESR1 (0.46) | ALDH1A1KDM4EHPGDL3MBTL1CYP1A1 | |
| SCHEMBL21312378 | 0.76 | HRH3 (0.52) | THRBHRH3DRD3ALDH1A1KDM4E | |
| SCHEMBL21312112 | 0.76 | HRH3 (0.52) | THRBHRH3DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101617251-A | Blooming | SUMITOMO CHEMICAL CO | 2009-12-30 | — | — | CN | disclosed |