Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758856 | 0.78 | — | — | |
| SCHEMBL19142972 | 0.70 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| SCHEMBL11465685 | 0.70 | ALDH1A1 (0.30) | ALDH1A1TDP1 | |
| SCHEMBL27574336 | 0.70 | SLC1A3 (0.37) | RNPEPALDH1A1TDP1 | |
| SCHEMBL11597205 | 0.69 | — | — | |
| SCHEMBL933146 | 0.67 | — | — | |
| SCHEMBL16983299 | 0.67 | — | — | |
| SCHEMBL3666766 | 0.67 | CHRM1 (0.58) | RNPEPTDP1 | |
| SCHEMBL11853324 | 0.65 | — | — | |
| SCHEMBL9517454 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622276-A | Antagonistic antibodies against EPHA2 for the treatment of cancer | SANOFI AVENTIS | 2010-01-06 | — | — | CN | claimed |
| CN-101616933-A | Novel anti-CD 38 antibodies for the treatment of cancer | SANOFI AVENTIS | 2009-12-30 | — | — | CN | claimed |
| CN-101622276-A | Antagonistic antibodies against EPHA2 for the treatment of cancer | SANOFI AVENTIS | 2010-01-06 | — | — | CN | disclosed |
| CN-101616933-A | Novel anti-CD 38 antibodies for the treatment of cancer | SANOFI AVENTIS | 2009-12-30 | — | — | CN | disclosed |