Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008665 | 0.87 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL2703150 | 0.83 | CA2 (0.48) | SLC1A3SLC1A2SLC1A1TDP1HDAC1 | |
| SCHEMBL9586717 | 0.81 | RNPEP (0.38) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL157028 | 0.78 | — | — | |
| SCHEMBL13225821 | 0.78 | ENPEP (0.40) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL7939626 | 0.78 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL2696819 | 0.77 | NAALAD2 (0.46) | SLC1A3SLC1A2SLC1A1HDAC1HDAC2 | |
| SCHEMBL3182058 | 0.76 | TDP1 (0.38) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL21225948 | 0.76 | TDP1 (0.38) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL21519882 | 0.76 | TDP1 (0.38) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1329614-A | Fused pyridazine derivatives, process for preparation of same and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-02 | — | — | CN | disclosed |