Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996977 | 0.81 | PFKFB3 (0.60) | HDAC1KITALDH1A1MEN1KMT2A | |
| SCHEMBL788023 | 0.76 | PFKFB3 (0.58) | HDAC1MEN1KMT2AGHSRPFKFB3 | |
| SCHEMBL16756206 | 0.76 | HDAC1 (0.62) | HDAC1SYKKITALDH1A1MEN1 | |
| SCHEMBL2689511 | 0.76 | CCR2 (0.54) | HDAC1ACLYALDH1A1MEN1KMT2A | |
| SCHEMBL5229344 | 0.76 | HDAC1 (0.51) | HDAC1SYKACLYKITMEN1 | |
| SCHEMBL5048183 | 0.73 | HDAC1 (0.60) | HDAC1KITALDH1A1GHSRMCL1 | |
| SCHEMBL5049402 | 0.72 | HDAC1 (0.67) | HDAC1KITALDH1A1MEN1KMT2A | |
| SCHEMBL788640 | 0.71 | HDAC1 (0.52) | HDAC1KITALDH1A1GHSRMCL1 | |
| SCHEMBL9569793 | 0.70 | EPHX2 (0.48) | HDAC1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4190648 | 0.69 | CCR2 (0.55) | HDAC1SYKACLYALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817767-A | Substituted sulphonamide compound and preparation method, medicine composition and application thereof | SHANGHAI INST BIOL SCIENCES | 2010-09-01 | — | — | CN | disclosed |