Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190648 | 0.82 | CCR2 (0.55) | HDAC1SYKCCR2CA2GHSR | |
| SCHEMBL16756206 | 0.81 | HDAC1 (0.62) | HDAC1SYKCCR2CA2GHSR | |
| SCHEMBL4188720 | 0.76 | CCR2 (0.64) | HDAC1CCR2CA2GHSRKIT | |
| SCHEMBL27790751 | 0.76 | HDAC1 (0.52) | HDAC1SYKCCR2CA2GHSR | |
| SCHEMBL9569793 | 0.75 | EPHX2 (0.48) | HDAC1CCR2CA2MEN1KMT2A | |
| SCHEMBL13653282 | 0.75 | MCL1 (0.56) | CCR2ACLYMCL1CDK1CCNB1 | |
| SCHEMBL5229993 | 0.75 | PPARG (0.55) | PPARGMEN1KMT2AP2RX1MAPT | |
| SCHEMBL13653320 | 0.74 | CCR2 (0.62) | HDAC1SYKCCR2CA2GHSR | |
| SCHEMBL5233621 | 0.74 | SMN1; SMN2 (0.53) | MEN1KMT2AP2RX1MAPTLMNA | |
| SCHEMBL5228507 | 0.73 | HTT (0.58) | MEN1KMT2AP2RX1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |