Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22261521 | 0.79 | ALDH1A1 (0.48) | EDNRBEDNRAMAPTNPC1RAB9A | |
| SCHEMBL28254055 | 0.79 | PTGS2 (0.64) | PTGS2PTGS1MAPTRAB9AKMT2A | |
| SCHEMBL8038496 | 0.78 | PTGS2 (0.51) | PTGS2APPEDNRBEDNRAABL1 | |
| SCHEMBL1181119 | 0.78 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL2781156 | 0.78 | PTGS2 (0.46) | PTGS2EDNRBEDNRAMAPTNPC1 | |
| Ammonia Solution, Strong SCHEMBL23908221 | 0.77 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL28914110 | 0.77 | NPC1 (0.50) | PTGS2APPABL1ABCB1BCR | |
| SCHEMBL3157739 | 0.74 | PTGS2 (0.51) | PTGS2BACE1MAPTNPC1RAB9A | |
| SCHEMBL7323658 | 0.74 | MAPK14 (0.50) | PTGS2PTGS1KDM4E | |
| SCHEMBL4450455 | 0.74 | ESR1 (0.46) | PTGS2APPABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668058-B1 | CONJUGATED POLYMERS, THEIR PREPARATION AND USE THEREOF | MERCK PATENT GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-7767785-B2 | Conjugated polymers, their preparation and use thereof | MERCK PATENT GMBH (DE) | 2010-08-03 | — | — | US | disclosed |
| US-20090014690-A1 | Conjugated polymers, their preparation and use thereof | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1668058-A1 | CONJUGATED POLYMERS, THEIR PREPARATION AND USE THEREOF | MERCK PATENT GmbH (DE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030828-A1 | CONJUGATED POLYMERS, THEIR PREPARATION AND USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-04-07 | — | — | WO | disclosed |
| WO-2001009117-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELLIX NEUROSCIENCE INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |