Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.71 |
| ▸ | CDK1 | P06493 | 14/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 14/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.58 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MGMT | P16455 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL200612 | 0.86 | CDK2 (0.68) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL135690 | 0.84 | CDK2 (1.00) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL432161 | 0.70 | PAK1 (0.66) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL29720347 | 0.70 | MAP3K5 (0.60) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL16146539 | 0.69 | HDAC1 (0.67) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| 2,6-Diaminopurine SCHEMBL28083713 | 0.69 | PDPK1 (0.79) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL8971208 | 0.69 | CDK1 (1.00) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL27870406 | 0.68 | PDPK1 (0.61) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL8618498 | 0.68 | CDK1 (0.77) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL30176198 | 0.68 | CDK1 (0.77) | CDK2CDK1CCNB1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101821277-A | Tetrahydropyran nucleic acid analogs | ISIS PHARMACEUTICALS INC | 2010-09-01 | — | — | CN | disclosed |