Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 10/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812765 | 0.84 | MAPT (0.37) | ELANETP53MAPTKMT2AL3MBTL1 | |
| SCHEMBL27964785 | 0.81 | MKNK1 (0.40) | ELANE | |
| SCHEMBL28825391 | 0.78 | ELANE (0.40) | ELANEMAPT | |
| SCHEMBL27893648 | 0.73 | BTK (0.37) | MAPTKMT2A | |
| SCHEMBL27621412 | 0.72 | ELANE (0.40) | ELANEMAPTKMT2A | |
| SCHEMBL6024351 | 0.72 | ELANE (0.63) | ELANETP53MAPTKMT2A | |
| SCHEMBL3264005 | 0.71 | SMN1; SMN2 (0.38) | SIRT2TP53MAPTKMT2AATM | |
| SCHEMBL3639047 | 0.70 | NPC1 (0.36) | SLC22A12SLC6A3TP53MAPTKMT2A | |
| SCHEMBL27808009 | 0.70 | ELANE (0.39) | ELANEMAPTKMT2A | |
| SCHEMBL27805740 | 0.70 | ELANE (0.39) | ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801963-A | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases | ASTRAZENECA AB | 2010-08-11 | — | — | CN | disclosed |