Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080711 | 0.80 | AKT1 (0.44) | AKT1ALDH1A1HPGDLMNACES1 | |
| SCHEMBL3297834 | 0.80 | AKT1 (0.44) | AKT1ALDH1A1HPGDLMNACES1 | |
| SCHEMBL18585106 | 0.80 | AKT1 (0.44) | AKT1ALDH1A1HPGDLMNACES1 | |
| SCHEMBL30680 | 0.78 | MAOA (0.48) | AKT1ALDH1A1HPGDLMNAPOLB | |
| Water SCHEMBL8670864 | 0.76 | MAOA (0.47) | AKT1ALDH1A1HPGDLMNAPOLB | |
| SCHEMBL11214238 | 0.76 | AKT1 (0.41) | AKT1ALDH1A1HPGDLMNACES1 | |
| Charcoal, Activated SCHEMBL9723289 | 0.76 | MAOA (0.47) | AKT1ALDH1A1HPGDLMNAPOLB | |
| SCHEMBL7886735 | 0.76 | AKT1 (0.41) | AKT1ALDH1A1HPGDLMNACES1 | |
| SCHEMBL367640 | 0.76 | AKT1 (0.58) | AKT1ALDH1A1HPGDLMNACES1 | |
| SCHEMBL10611184 | 0.76 | ALDH1A1 (0.42) | AKT1ALDH1A1HPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957127-B1 | HYDROPHILIC COATING COMPOSITION FOR URINARY CATHETER | DSM IP ASSETS BV (NL) | 2018-02-21 | — | — | EP | claimed |
| US-20140194486-A1 | THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2014-07-10 | — | — | US | claimed |
| US-8133580-B2 | Coating composition for a urinary catheter | DSM IP ASSETS B.V. (NL) | 2012-03-13 | — | — | US | claimed |
| EP-2315749-A2 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2011-05-04 | — | — | EP | claimed |
| WO-2009156735-A2 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-30 | — | — | WO | claimed |
| US-20090306244-A1 | STERILISATION OF A MEDICAL DEVICE BY IRRADIATION | DSM IP ASSETS B.V. (NL) | 2009-12-10 | — | — | US | claimed |
| US-20090155575-A1 | COATING COMPOSITION FOR A URINARY CATHETER | DSM IP ASSETS B.V. (NL) | 2009-06-18 | — | — | US | claimed |
| EP-2035045-A1 | STERILISATION OF A MEDICAL DEVICE BY IRRADIATION | DSMIP Assets B.V. (NL) | 2009-03-18 | — | — | EP | claimed |
| EP-1957127-A2 | HYDROPHILIC COATING COMPOSITION FOR URINARY CATHETER | DSMIP Assets B.V. (NL) | 2008-08-20 | — | — | EP | claimed |
| WO-2007137699-A1 | STERILISATION OF A MEDICAL DEVICE BY IRRADIATION | DSM IP ASSETS B.V. (NL) | 2007-12-06 | — | — | WO | claimed |
| CN-1044350-A | BIPOLAR LIQUID ELECTROSTATIC DEVELOPER | DU PONT (US) | 1990-08-01 | — | — | CN | claimed |
| CN-1044349-A | Organic compounds containing sulfur as adjuvants for positive electro-static liquid developers | DU PONT (US) | 1990-08-01 | — | — | CN | claimed |
| EP-0300526-A2 | Antiviral pharmaceutical compositions containing cyclodextrins | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-25 | — | — | EP | claimed |
| US-4772699-A | STABILIZERS FOR POLYPROPYLENE | AUSIMONT S.P.A. (IT) | 1988-09-20 | — | — | US | claimed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0229655-A2 | Morpholine derivatives containing substituted piperidine groups and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1987-07-22 | — | — | EP | claimed |
| US-4401817-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1983-08-30 | — | — | US | claimed |
| US-4338329-A | COMBATTING RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | claimed |
| US-4289782-A | PARTICULARLY FOR INHIBITING GROWTH OF RHINOVIRUSES | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | claimed |
| US-4230868-A | α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles | ELI LILLY AND COMPANY (US) | 1980-10-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194486-A1 | THERAPEUTIC AGENTS | TP53, MDM2, TP53BP1 | AKT1 188/4885ALDH1A1 2445/4885HPGD 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.