Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814208 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KMT2ATDP1MEN1SMN1; SMN2 | |
| SCHEMBL27814220 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ATDP1MEN1L3MBTL1 | |
| SCHEMBL31725 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KMT2ATDP1MEN1HPRT1 | |
| SCHEMBL29848512 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KMT2ATDP1MEN1HPRT1 | |
| SCHEMBL30443747 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KMT2ATDP1MEN1HPRT1 | |
| SCHEMBL27793073 | 0.73 | SCN2A (0.49) | ALDH1A1KMT2ATDP1POLBMEN1 | |
| SCHEMBL27792987 | 0.72 | NPC1 (0.43) | ALDH1A1KMT2ATDP1POLBMEN1 | |
| SCHEMBL15821069 | 0.70 | HPRT1 (0.65) | ALDH1A1KMT2ATDP1MEN1HPRT1 | |
| SCHEMBL6367092 | 0.70 | TDP1 (0.50) | ALDH1A1KMT2ATDP1MEN1L3MBTL1 | |
| SCHEMBL17841980 | 0.70 | HPRT1 (0.65) | ALDH1A1KMT2ATDP1MEN1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817774-B | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2012-03-21 | — | — | CN | disclosed |
| CN-101817774-A | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2010-09-01 | — | — | CN | disclosed |