Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793080 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27814220 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TDP1KMT2AMAPTMAPK1 | |
| SCHEMBL27793073 | 0.80 | SCN2A (0.49) | ALDH1A1TDP1KMT2ALMNAMAPT | |
| SCHEMBL27792987 | 0.79 | NPC1 (0.43) | ALDH1A1TDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27793176 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27793064 | 0.77 | POLB (0.56) | ALDH1A1TDP1KMT2ALMNAHTT | |
| SCHEMBL6367092 | 0.77 | TDP1 (0.50) | ALDH1A1TDP1KMT2AHTTL3MBTL1 | |
| SCHEMBL27814221 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TDP1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1321811 | 0.74 | KMT2A (0.74) | ALDH1A1KMT2AHCAR1HTTMAPT | |
| SCHEMBL13303553 | 0.73 | KMT2A (0.46) | ALDH1A1TDP1KMT2AHCAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817774-B | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2012-03-21 | — | — | CN | disclosed |
| CN-101817774-A | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2010-09-01 | — | — | CN | disclosed |