Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355572 | 0.87 | CYP2D6 (0.33) | KDM4EMAPTCYP1A2CYP2D6CYP19A1 | |
| SCHEMBL585219 | 0.85 | NR5A1 (0.43) | KDM4EMAPTL3MBTL1LTA4HCYP1A2 | |
| SCHEMBL588822 | 0.85 | NR5A1 (0.43) | KDM4EMAPTL3MBTL1LTA4HCYP1A2 | |
| Pyridine SCHEMBL28010655 | 0.82 | CYP2D6 (0.52) | LSSKDM4EMAPTLMNAL3MBTL1 | |
| SCHEMBL585087 | 0.81 | — | — | |
| SCHEMBL27814703 | 0.80 | CHRNB2 (0.36) | LSSKDM4EHDAC3HDAC4HDAC1 | |
| SCHEMBL14806869 | 0.78 | MAOA (0.40) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14806854 | 0.78 | MAOA (0.40) | HRH3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4219044 | 0.78 | LSS (0.59) | LSSHRH3KCNA3KCNH2HRH1 | |
| SCHEMBL14806861 | 0.77 | MAOA (0.39) | HRH3HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101851256-B | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | UNIV GUANGDONG PHARM | 2013-01-09 | — | — | CN | disclosed |
| CN-101851256-A | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY | 2010-10-06 | — | — | CN | disclosed |