Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444791 | 0.90 | TXNRD1 (0.49) | ALDH1A1LMNAHTTTXNRD1TXNRD3 | |
| SCHEMBL27773797 | 0.86 | SLC6A4 (0.47) | KMT2A | |
| SCHEMBL27773666 | 0.78 | GAA (0.43) | ALDH1A1LMNAPKMTDP1KMT2A | |
| SCHEMBL4446772 | 0.77 | TXNRD1 (0.49) | ALDH1A1LMNATDP1TXNRD1TXNRD3 | |
| SCHEMBL215804 | 0.76 | TDP1 (0.58) | ALDH1A1HPGDLMNATTRHTT | |
| SCHEMBL30780913 | 0.76 | TDP1 (0.58) | ALDH1A1HPGDLMNATTRHTT | |
| SCHEMBL4437981 | 0.74 | SLC6A4 (0.53) | APOBEC3G | |
| SCHEMBL4437976 | 0.74 | SLC6A2 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL357288 | 0.73 | HTT (0.60) | ALDH1A1HPGDLMNATTRHTT | |
| SCHEMBL6521172 | 0.73 | TXNRD1 (0.46) | ALDH1A1LMNAHTTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622227-A | Biaryl and biheteroaryl compounds useful in treating iron disorders | XENON PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | disclosed |