SCHEMBL27795145

SCHEMBL27795145

CCCCCC[Si](CCCCCC)(OC(C)C)OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.38
LMNA P02545 2/20 0.38
DNM1 Q05193 9/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36
EPHX1 P07099 1/20 0.36
TRPM8 Q7Z2W7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20658098 0.98 LMNA (0.34) TSHRTHRBLMNADNM1MEN1
SCHEMBL706677 0.93 LMNA (0.30) LMNA
SCHEMBL28256604 0.91 LMNA (0.35) TSHRTHRBLMNADNM1MEN1
SCHEMBL105859 0.90 LMNA (0.31) TSHRLMNA
Fluoride SCHEMBL27813665 0.89 LMNA (0.34) TSHRTHRBLMNADNM1MEN1
SCHEMBL705979 0.88 LMNA (0.30) LMNA
SCHEMBL704511 0.88 LMNA (0.30) LMNA
SCHEMBL702203 0.88
SCHEMBL704077 0.83
SCHEMBL284378 0.82 LMNA (0.35) TSHRTHRBLMNADNM1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed