Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339922 | 0.97 | GPBAR1 (0.43) | GPBAR1PTGDR2RXRARXRBFFAR4 | |
| SCHEMBL30509082 | 0.97 | GPBAR1 (0.43) | GPBAR1PTGDR2RXRARXRBFFAR4 | |
| SCHEMBL3339754 | 0.88 | GPBAR1 (0.41) | GPBAR1PTGDR2RORC | |
| SCHEMBL30509078 | 0.88 | GPBAR1 (0.41) | GPBAR1PTGDR2RORC | |
| SCHEMBL16390861 | 0.87 | GPBAR1 (0.41) | GPBAR1RXRARXRBFFAR4RORC | |
| SCHEMBL3339509 | 0.83 | RXRA (0.43) | GPBAR1PTGDR2RXRARXRBRORC | |
| SCHEMBL16858742 | 0.83 | RXRA (0.38) | GPBAR1PTGDR2RXRARXRBFFAR4 | |
| SCHEMBL3335704 | 0.82 | GPBAR1 (0.50) | GPBAR1RORC | |
| SCHEMBL11263458 | 0.81 | GPBAR1 (0.45) | GPBAR1PTGDR2 | |
| SCHEMBL3337439 | 0.81 | GPBAR1 (0.44) | GPBAR1PTGDR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101678007-B | Gonadotropin-releasing hormone receptor antagonists and its pharmaceutical application | NEUROCRINE BIOSCIENCES INC | 2013-07-03 | — | — | CN | disclosed |
| CN-101678007-A | gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES INC | 2010-03-24 | — | — | CN | disclosed |