Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | F13A1 | P00488 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260711 | 0.96 | GPBAR1 (0.46) | GPBAR1PTGDR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11260689 | 0.92 | GPBAR1 (0.47) | GPBAR1PTGDR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11259485 | 0.87 | LTB4R (0.44) | ALDH1A1TMEM97SIGMAR1LTB4RMAPT | |
| SCHEMBL3337091 | 0.86 | GPBAR1 (0.38) | GPBAR1PTGDR2SLC6A2SLC6A4SLC6A3 | |
| Benzylamine SCHEMBL11271042 | 0.84 | GPBAR1 (0.44) | GPBAR1PTGDR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11255842 | 0.83 | ALDH1A1 (0.40) | SLC6A3ALDH1A1TMEM97SIGMAR1LTB4R | |
| SCHEMBL11257623 | 0.81 | HDAC3 (0.45) | SLC6A3ALDH1A1KDM4ELTB4RMAPT | |
| SCHEMBL11267339 | 0.80 | POLB (0.43) | GPBAR1PTGDR2SLC6A4TSHRALDH1A1 | |
| SCHEMBL11267185 | 0.79 | GPBAR1 (0.48) | GPBAR1ALDH1A1 | |
| SCHEMBL11503510 | 0.79 | GPBAR1 (0.44) | GPBAR1PTGDR2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003532-B1 | OMEGA-(2-(N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS, THEIR USE AND PREPARATION, AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |
| EP-0003532-A1 | Omega-(2-(N-lower alkyl-benzamido)-phenyl)-alkanoic acids, their use and preparation, and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |