Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 8/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16390905 | 0.97 | SLC16A3 (0.59) | SLC16A3HDAC1HDAC8HDAC6SUCNR1 | |
| SCHEMBL3336081 | 0.84 | SLC16A3 (0.53) | SLC16A3HDAC1HDAC8HDAC6NR1H4 | |
| SCHEMBL3337087 | 0.81 | SLC16A3 (0.42) | SLC16A3HDAC1HDAC8HDAC6 | |
| SCHEMBL2229279 | 0.79 | SLC16A3 (0.54) | SLC16A3HDAC1NR1H4PPARG | |
| SCHEMBL31661766 | 0.79 | SLC16A3 (0.54) | SLC16A3HDAC1NR1H4PPARG | |
| SCHEMBL31661740 | 0.79 | LMNA (0.56) | SLC16A3SUCNR1F11PPARG | |
| SCHEMBL2061475 | 0.79 | LMNA (0.56) | SLC16A3SUCNR1F11PPARG | |
| SCHEMBL3554633 | 0.76 | SLC16A3 (1.00) | SLC16A3 | |
| SCHEMBL31661816 | 0.74 | SMN1; SMN2 (0.53) | SLC16A3PPARG | |
| SCHEMBL13349339 | 0.73 | MAPT (0.59) | HDAC1HDAC8HDAC6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101678007-B | Gonadotropin-releasing hormone receptor antagonists and its pharmaceutical application | NEUROCRINE BIOSCIENCES INC | 2013-07-03 | — | — | CN | disclosed |
| CN-101678007-A | gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES INC | 2010-03-24 | — | — | CN | disclosed |