SCHEMBL31661740

SCHEMBL31661740

O=C(O)CCCc1ccccc1NC(=O)c1cccc(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
SLC16A3 O15427 5/20 0.54
KCNK3 O14649 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
ABL1 P00519 1/20 0.50
TSHR P16473 1/20 0.50
RIN1 Q13671 1/20 0.50
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
GRIK1 P39086 1/20 0.48
SUCNR1 Q9BXA5 2/20 0.47
ABCB1 P08183 1/20 0.47
CFD P00746 1/20 0.46
F11 P03951 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2061475 1.00 LMNA (0.56) LMNASLC16A3KCNK3KCNK9MAPT
SCHEMBL2229279 0.86 SLC16A3 (0.54) SLC16A3MEN1KMT2APPARGPPARA
SCHEMBL31661766 0.86 SLC16A3 (0.54) SLC16A3MEN1KMT2APPARGPPARA
SCHEMBL16390905 0.82 SLC16A3 (0.59) SLC16A3PPARGSUCNR1F11
SCHEMBL31661727 0.81 SLC16A3 (0.46) LMNASLC16A3MAPTMEN1KMT2A
SCHEMBL5657531 0.81 SLC16A3 (0.46) LMNASLC16A3MAPTMEN1KMT2A
SCHEMBL27795243 0.79 SLC16A3 (0.61) SLC16A3PPARGSUCNR1F11
SCHEMBL13814818 0.79 NR1H4 (0.58) LMNAMAPTMEN1KMT2ANPC1
SCHEMBL31661816 0.78 SMN1; SMN2 (0.53) SLC16A3MEN1KMT2ATDP1PPARG
SCHEMBL16397110 0.78 KCNK3 (0.53) LMNAKCNK3KCNK9MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed