Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CD69 | Q07108 | 1/20 | 0.55 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.54 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.54 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975663 | 1.00 | ALDH1A1 (0.57) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL18300871 | 0.94 | CD69 (0.55) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL900637 | 0.93 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL8645253 | 0.93 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL900939 | 0.93 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL27686935 | 0.93 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL16056935 | 0.93 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL18592624 | 0.91 | CD69 (0.54) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL24260401 | 0.90 | CD69 (0.53) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL6244373 | 0.90 | CD69 (0.53) | ALDH1A1THRBMAPK1CD69LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101984047-A | WecA gene knock-out train, its preparing method, application and method for screening M.tuberculosis (MTB) N-acetylglucosamine-1-phosphate transferase inhibitor | UNIV DALIAN MEDICAL | 2011-03-09 | — | — | CN | disclosed |
| CN-101942501-A | Method for filtering mycobacterium tuberculosis glucosamine-1-phosphate acetyltransferase inhibitors with high throughput | UNIV DALIAN MEDICAL | 2011-01-12 | — | — | CN | disclosed |
| CN-101928691-A | glmM gene knock-out bacterial strain as well as preparation method and application in sieving mycobacterium tuberculosis phosphoglucomutase inhibitors | UNIV DALIAN MEDICAL | 2010-12-29 | — | — | CN | disclosed |
| CN-101845480-A | High throughput screening method of mycobacterium tuberculosis alpha-D-glucose-1-thymine phosphate transferase inhibitor | UNIV DALIAN MEDICAL | 2010-09-29 | — | — | CN | disclosed |