Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CD69 | Q07108 | 1/20 | 0.60 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.60 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.60 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900939 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL900637 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL16056935 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL8645253 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL9546525 | 0.93 | ALDH1A1 (0.57) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL27795575 | 0.93 | ALDH1A1 (0.57) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL27975663 | 0.93 | ALDH1A1 (0.57) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL18300844 | 0.92 | LGALS3 (0.60) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL30747496 | 0.91 | ALDH1A1 (0.55) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL4726917 | 0.90 | CD69 (0.65) | ALDH1A1THRBMAPK1CD69LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405355-A | Process for the preparation of fluoroketolides | 森普拉制药公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-102614207-B | 18 membered macrocycles and analog thereof | OPTIMER BIOTECHNOLOGY INC. (US) | 2016-01-13 | — | — | CN | disclosed |
| CN-102614207-A | 18-membered ring macrocyclic compound and analogues thereof | OPTIMER BIOTECHNOLOGY INC | 2012-08-01 | — | — | CN | disclosed |
| CN-101128114-B | 18-membered ring macrocycles and analogs thereof | HAODING SHENGJI COMPANY | 2012-03-28 | — | — | CN | disclosed |
| CN-101180307-A | Ionic liquid supported synthesis | UNIV MCGILL (CA) | 2008-05-14 | — | — | CN | disclosed |
| CN-101128114-A | 18-membered ring macrocycles and analogs thereof | HAODING SHENGJI COMPANY (US) | 2008-02-20 | — | — | CN | disclosed |