Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680891 | 0.82 | MEN1 (0.79) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL30612630 | 0.81 | POLB (0.75) | MEN1KMT2APOLBLMNAGAA | |
| SCHEMBL247350 | 0.81 | POLB (0.75) | MEN1KMT2APOLBLMNAGAA | |
| SCHEMBL4005240 | 0.79 | GAA (0.71) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL29678338 | 0.79 | HPGD (0.62) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL5858216 | 0.79 | HPGD (0.62) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7761150 | 0.78 | KDM4E (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27570593 | 0.77 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL25358934 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL29528302 | 0.76 | ALDH1A1 (0.73) | MEN1KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102314-B | Benzothiazole, benzoglyoxaline, benzoxazole derivative and its production and use | SICHUAN UNIVERSITY (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103102314-A | Benzothiazole, benzimidazole, benzoxazole derivatives and preparation method and application thereof | UNIV SICHUAN | 2013-05-15 | — | — | CN | disclosed |
| CN-101891704-B | N-(2-(2-amine)oxyethylthiobenzothiazole-6-)-2-formamide derivative as well as preparation method and applciaiton thereof | UNIV SICHUAN | 2012-07-04 | — | — | CN | disclosed |
| CN-101891704-A | N-(2-(2-amine)oxyethylthiobenzothiazole-6-)-2-formamide derivative as well as preparation method and applciaiton thereof | UNIV SICHUAN | 2010-11-24 | — | — | CN | disclosed |