Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797003 | 0.82 | LMNA (0.37) | TSHRCYP3A4CA2KDM4ESLC7A5 | |
| SCHEMBL27797027 | 0.79 | NPSR1 (0.43) | TSHRCYP3A4 | |
| SCHEMBL8041633 | 0.75 | TSHR (0.39) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL8041628 | 0.75 | TSHR (0.38) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL28183514 | 0.75 | TSHR (0.45) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL6257483 | 0.75 | TSHR (0.45) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL21124173 | 0.73 | TSHR (0.44) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL9439765 | 0.73 | TSHR (0.44) | TSHRCPN1CPB2TP53CYP3A4 | |
| SCHEMBL17064430 | 0.72 | HRH1 (0.48) | TSHRCPN1CPB2KDM4E | |
| SCHEMBL20921369 | 0.72 | TSHR (0.42) | TSHRCPN1CPB2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679215-A | New benzamide derivatives as the follicle stimulating hormone conditioning agent | ADDEX PHARMA SA | 2010-03-24 | — | — | CN | disclosed |