Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044822 | 0.87 | CPN1 (0.41) | CPN1CPB2THRBFKBP1ATP53 | |
| SCHEMBL4595927 | 0.84 | THRB (0.44) | TSHRTHRBTHRAHPGDPOLB | |
| SCHEMBL8041633 | 0.82 | TSHR (0.39) | TSHRCPN1CPB2FKBP1ATP53 | |
| SCHEMBL651280 | 0.80 | THRB (0.46) | TSHRTHRBTHRAHPGDPOLB | |
| SCHEMBL9402077 | 0.79 | THRB (0.48) | THRBTHRAPOLB | |
| SCHEMBL4970630 | 0.79 | THRB (0.48) | THRBTHRAPOLB | |
| SCHEMBL8086548 | 0.79 | THRB (0.48) | THRBTHRAPOLB | |
| SCHEMBL342568 | 0.79 | THRB (0.48) | THRBTHRAPOLB | |
| SCHEMBL342683 | 0.77 | NPSR1 (0.48) | HPGDCYP3A4 | |
| SCHEMBL29799953 | 0.77 | NPSR1 (0.48) | HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | disclosed |