Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16965622 | 0.82 | ALDH1A1 (0.38) | ALDH1A1POLBHSD11B1HPGDNPC1 | |
| SCHEMBL27818382 | 0.81 | ALDH1A1 (0.41) | GPR119ALDH1A1POLBHSD11B1HPGD | |
| SCHEMBL28829189 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDNPC1MAPT | |
| SCHEMBL22978675 | 0.79 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HPGDNPC1 | |
| SCHEMBL12282193 | 0.78 | ALDH1A1 (0.45) | GPR119ALDH1A1POLBHSD11B1HPGD | |
| SCHEMBL12283406 | 0.78 | ALDH1A1 (0.45) | GPR119ALDH1A1POLBHSD11B1HPGD | |
| SCHEMBL390019 | 0.78 | ALDH1A1 (0.45) | GPR119ALDH1A1POLBHSD11B1HPGD | |
| SCHEMBL16965427 | 0.78 | MEN1 (0.43) | ALDH1A1POLBHPGDHTTRAB9A | |
| SCHEMBL27150333 | 0.77 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL22978699 | 0.76 | ALDH1A1 (0.44) | ALDH1A1POLBHSD11B1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896481-A | Pyrimidyl indoline compound | DAIICHI SANKYO CO LTD | 2010-11-24 | — | — | CN | disclosed |