Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12282193 | 1.00 | ALDH1A1 (0.45) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL12283406 | 1.00 | ALDH1A1 (0.45) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL5412873 | 0.98 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL2654623 | 0.93 | TSHR (0.40) | ALDH1A1POLBHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL10365765 | 0.84 | ALDH1A1 (0.44) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL22978699 | 0.84 | ALDH1A1 (0.44) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL16965092 | 0.84 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL22978675 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL29116529 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL6886633 | 0.83 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415381-A | Thiazolopyridine derivatives as GPR119 agonist | 人类制药有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109415359-A | heterocyclic GPR119 agonist compounds | 人类制药有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-105189498-B | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | 默沙东公司 | 2017-06-27 | — | — | CN | claimed |
| CN-101801954-B | Compounds and compositions as modulators of GPR119 activity | IRM LLC | 2013-10-09 | — | — | CN | claimed |
| CN-103328482-A | New bicyclic compound for modulating G protein-coupled receptors | HANMI PHARM IND CO LTD | 2013-09-25 | — | — | CN | claimed |
| CN-102918027-A | Modulators of the gpr119 receptor and the treatment of disorders related thereto | ARENA PHARM INC | 2013-02-06 | — | — | CN | claimed |
| CN-102803255-A | Novel GPR 119 agonists | CADILA HEALTHCARE LTD | 2012-11-28 | — | — | CN | claimed |
| CN-101679258-A | 4-piperidinylurea compounds as soluble epoxide hydrolase inhibitors | ARETE THERAPEUTICS INC | 2010-03-24 | — | — | CN | claimed |
| US-20070232559-A1 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-10-04 | — | — | US | claimed |
| WO-2024206514-A1 | COUMARIN PHOTOBASE GENERATORS FOR POLYIMIDE FORMATION | NITTO DENKO CORPORATION (JP) | 2024-10-03 | — | — | WO | disclosed |
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023020519-A1 | 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-23 | — | — | WO | disclosed |
| WO-2022188729-A1 | FUSED RING DERIVATIVES USEFUL AS KRAS G12D INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |
| CN-114514023-A | Methods of treating pancreatic cancer using RAD51 inhibitors | 赛泰尔治疗公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2005007647-A1 | TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| CN-1265661-A | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| CN-1061595-A | Be used as new heterocyclics of excited amino acid receptor antagonists and its production and use | AKTIEBOTAGEL ASTRA (SE) | 1992-06-03 | — | — | CN | disclosed |
| US-4234484-A | FROM ALKOXYLATED CYCLIC AMIDES USING AS A CATALYST A QUATERNARY AMMONIUM OR ALKALI METAL SALT OF TETRAFLUOROBORIC OR HEXAFLUOROPHOSPHORIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| US-4149941-A | ELECTROLYTIC ALKOXYLATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4118500-A | Fungicidal alkoxy mono- and dialkoxy N-substituted cyclic amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232559-A1 | 2-PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY AND COMPOSITIONS THEREOF | ADORA2A, ADORA3, ADORA1 | ALDH1A1 635/4885POLB 2203/4885HSD11B1 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.