Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799051 | 1.00 | CYP1A1 (0.38) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL27955312 | 0.93 | NFE2L2 (0.40) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL4170999 | 0.87 | NFE2L2 (0.43) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL4170993 | 0.87 | NFE2L2 (0.43) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL4183387 | 0.86 | CYP1A1 (0.54) | CYP1A1CYP1A2CYP1B1KDM4ETAAR1 | |
| SCHEMBL4183390 | 0.86 | CYP1A1 (0.54) | CYP1A1CYP1A2CYP1B1KDM4ETAAR1 | |
| Ammonia Solution, Strong SCHEMBL27776433 | 0.85 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL27776420 | 0.84 | CYP1A1 (0.40) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL28782912 | 0.80 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1KDM4ELMNA | |
| SCHEMBL4161352 | 0.79 | TAAR1 (0.45) | TAAR1HDAC4MEF2DHTR6CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101686665-B | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-04-23 | — | — | CN | claimed |
| CN-101686665-A | styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2010-03-31 | — | — | CN | claimed |
| CN-101686665-A | styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2010-03-31 | — | — | CN | disclosed |