SCHEMBL4183387

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4183390	1.00	CYP1A1 (0.54)	CYP1A1CYP1B1CYP1A2APPTAAR1
	SCHEMBL8799051	0.86	CYP1A1 (0.38)	CYP1A1CYP1B1CYP1A2TAAR1KDM4E
	SCHEMBL27797271	0.86	CYP1A1 (0.38)	CYP1A1CYP1B1CYP1A2TAAR1KDM4E
	SCHEMBL8799920	0.86	NFE2L2 (0.58)	CYP1A1CYP1B1CYP1A2NFE2L2CYP19A1
	SCHEMBL27797359	0.85	MTNR1A (0.46)	CYP1A1CYP1B1CYP1A2APPKDM4E
	SCHEMBL8800149	0.85	MTNR1A (0.46)	CYP1A1CYP1B1CYP1A2APPKDM4E
	SCHEMBL4414963	0.84	CYP1A1 (0.58)	CYP1A1CYP1B1CYP1A2APPNFE2L2
	SCHEMBL4175333	0.83	TAAR1 (0.59)	CYP1A1CYP1B1CYP1A2TAAR1NFE2L2
	Ammonia Solution, Strong SCHEMBL27955299	0.83	CYP1A1 (0.56)	CYP1A1CYP1B1CYP1A2APPNFE2L2
	SCHEMBL4175338	0.83	TAAR1 (0.59)	CYP1A1CYP1B1CYP1A2TAAR1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.