SCHEMBL27797385

SCHEMBL27797385

N#CCC(O)c1cc(Br)cc(CN)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27814860 0.82 IDO1 (0.32) IDO1
SCHEMBL27797263 0.78 IDO1 (0.33) IDO1
SCHEMBL237927 0.77
SCHEMBL4175801 0.77 TACR1 (0.31)
SCHEMBL4169011 0.77 CES2 (0.30)
SCHEMBL233043 0.73 PBRM1 (0.37)
SCHEMBL234828 0.71 SLC18A3 (0.41) IDO1
SCHEMBL7148283 0.70 BLM (0.47)
SCHEMBL28791999 0.70 ADRB2 (0.34)
SCHEMBL2547851 0.70 IGF1R (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101686665-A styrenyl derivative compounds for treating ophthalmic diseases and disorders ACUCELA INC 2010-03-31 CN disclosed