SCHEMBL277974

SCHEMBL277974

O=C(CCSc1ccccn1)ON1C(=O)CCC1=O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
KMT2A Q03164 3/20 0.52
MAPT P10636 2/20 0.52
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
HPGD P15428 2/20 0.45
LMNA P02545 2/20 0.45
MEN1 O00255 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PKM P14618 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30498662 1.00 ALDH1A1 (0.56) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL20983700 0.93 ALDH1A1 (0.50) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL29130297 0.90 ALDH1A1 (0.48) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL42368 0.88 ALDH1A1 (0.44) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL29352062 0.88 ALDH1A1 (0.44) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL28707482 0.86 ALDH1A1 (0.57) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL1923934 0.85 HPGD (0.53) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL10980056 0.84 KMT2A (0.41) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL29356575 0.83 ALDH1A1 (0.39) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL107907 0.83 ALDH1A1 (0.39) ALDH1A1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281628-A1 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-11 US claimed
EP-4392087-A2 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-03 EP claimed
WO-2023028082-A2 COMPOSITE NANOPARTICULATE MINERALIZED COLLAGEN GLYCOSAMINOGLYCAN MATERIALS WITH TIME RELEASE ANTI-RESORPTIVE FACTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-02 WO claimed
EP-2804631-B1 SURROBODY CONJUGATES I2 PHARMACEUTICALS INC (US) 2021-03-17 EP claimed
EP-3275461-A1 PROTEIN-BASED THERAPY AND DIAGNOSIS OF TAU-MEDIATED PATHOLOGY IN ALZHEIMER'S DISEASE FIELD Axon Neuroscience SE (CY) 2018-01-31 EP claimed
US-9744241-B2 Method for nucleic acid delivery using hyaluronic acid SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-29 US claimed
US-20140294752-A1 METHOD FOR NUCLEIC ACID DELIVERY USING HYALURONIC ACID Research & Business Foundation Sungkyunkwan University (KR) 2014-10-02 US claimed
WO-2009077438-A1 METHOD FOR PREPARING PROTEIN CONJUGATES GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2009-06-25 WO claimed
EP-1578450-A4 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRAL (AU) 2009-06-17 EP claimed
EP-1701968-A4 IMMUNOGENIC PEPTIDE CARRIER CONJUGATES AND METHODS OF PRODUCING SAME WYETH CORP (US) 2007-10-03 EP claimed
EP-1206251-A4 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES ACCESS PHARMACEUTICALS AUSTRAL (AU) 2004-06-30 EP claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed
EP-1206251-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2002-05-22 EP claimed
WO-2000066090-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES BIOTECH AUSTRALIA PTY LIMITED (AU) 2000-11-09 WO claimed
EP-0473689-B1 THROMBUS-TARGETED COMPLEXES OF PLASMINOGEN ACTIVATOR AND FIBRIN FRAGMENTS UNIV TEMPLE (US) 1994-12-14 EP claimed
EP-0308936-B1 Antibody heteroconjugates for the killing of HIV-infected cells BRISTOL MYERS SQUIBB CO (US) 1994-07-06 EP claimed
EP-0184701-B1 A method for determining a ligand HOECHST CELANESE CORP (US) 1994-06-08 EP claimed
EP-0440647-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1991-08-14 EP claimed
WO-1989012110-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1989-12-14 WO claimed
EP-0184701-A2 A method for determining a ligand HOECHST CELANESE CORPORATION (US) 1986-06-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140294752-A1 METHOD FOR NUCLEIC ACID DELIVERY USING HYALURONIC ACID CD44, DNASE1, HNRNPH3 ALDH1A1 1523/4885KMT2A 2619/4885MAPT 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.