Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340343 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30498662 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL277974 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10340185 | 0.83 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10340287 | 0.82 | HDAC1 (0.41) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10340513 | 0.81 | HDAC1 (0.42) | ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL20983700 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL22203070 | 0.77 | LMNA (0.40) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29430092 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29130297 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114073775-A | Combination therapy for delivery across the blood brain barrier | 比奥阿赛斯技术有限公司 | 2022-02-22 | — | — | CN | disclosed |