SCHEMBL27797705

SCHEMBL27797705

CCOC(=O)CC=C1CC2CCC1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.38
SLC6A3 Q01959 4/20 0.35
SLC6A4 P31645 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ESR1 P03372 1/20 0.32
TRPA1 O75762 1/20 0.31
KDM4E B2RXH2 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP2D6 P10635 2/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688998 0.85 SLC6A3 (0.43) EPHX2SLC6A3SLC6A4MGAMGAA
SCHEMBL29635938 0.80 ESR2 (0.43) EPHX2SLC6A3SLC6A4ALDH1A1ESR1
SCHEMBL8681546 0.78 SLC6A3 (0.37) SLC6A3SLC6A4
SCHEMBL397866 0.73 SLC6A3 (0.31) SLC6A3
SCHEMBL31332791 0.70 SLC6A3 (0.42) SLC6A3SLC6A4ESR1
SCHEMBL11244400 0.70 SLC6A3 (0.39) EPHX2SLC6A3SLC6A4ALDH1A1KMT2A
SCHEMBL9126560 0.70 SLC6A3 (0.31) SLC6A3
SCHEMBL11216817 0.69
SCHEMBL9384024 0.69 EPHX2 (0.39) EPHX2SLC6A3SLC6A4ALDH1A1KMT2A
SCHEMBL3703757 0.68 ESR2 (0.42) ALDH1A1ESR1KDM4ECHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101663331-B Use of a combination chain transfer and activating agent to control molecular weight and optical density of pd catalyzed norbornene polymers PROMERUS LLC 2012-08-29 CN disclosed
CN-101663331-A Use of a combination chain transfer and activating agent to control molecular weight and optical density of pd catalyzed norbornene polymers PROMERUS LLC 2010-03-03 CN disclosed