Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239464 | 0.80 | SLC6A3 (0.53) | SLC6A3SLC6A4MAPTKMT2ATSHR | |
| SCHEMBL654652 | 0.77 | SLC6A3 (0.40) | SLC6A3SLC6A4KDM4EALOX15MEN1 | |
| SCHEMBL11245895 | 0.77 | SLC6A3 (0.40) | SLC6A3SLC6A4KDM4ELMNAMAPT | |
| SCHEMBL5429764 | 0.74 | LMNA (0.47) | SLC6A3KDM4ELMNAMAPTALOX15 | |
| SCHEMBL2328254 | 0.74 | LMNA (0.47) | SLC6A3KDM4ELMNAMAPTALOX15 | |
| SCHEMBL29635938 | 0.73 | ESR2 (0.43) | SLC6A3SLC6A4EPHX2KDM4ELMNA | |
| SCHEMBL27864843 | 0.73 | ESR2 (0.43) | SLC6A3SLC6A4EPHX2KDM4ELMNA | |
| SCHEMBL31296900 | 0.73 | LMNA (0.50) | KDM4ELMNAMAPTALOX15MEN1 | |
| SCHEMBL19229905 | 0.72 | GRM1 (0.39) | SLC6A3GRM1KDM4ELMNAMAPT | |
| SCHEMBL384569 | 0.71 | SLC6A3 (0.39) | SLC6A3SLC6A4TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349552-A | TREATMENT OF CANCER | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-09-14 | — | — | US | claimed |
| EP-0010941-B1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-12 | — | — | EP | claimed |
| EP-0010941-A1 | 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | claimed |