Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867067 | 0.80 | SNCA (0.53) | SNCALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL29214102 | 0.80 | SNCA (0.53) | SNCALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27797789 | 0.80 | SNCA (0.51) | SNCALMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1208152 | 0.78 | SNCA (0.86) | SNCALMNASMN1; SMN2GAAMAPT | |
| SCHEMBL29850622 | 0.78 | SNCA (0.86) | SNCALMNASMN1; SMN2GAAMAPT | |
| SCHEMBL8226386 | 0.77 | SNCA (0.78) | SNCAALDH1A1GAAMAPTSIRT2 | |
| SCHEMBL27750061 | 0.76 | NOX1 (0.48) | SNCALMNAALDH1A1GAAMAPT | |
| SCHEMBL27750062 | 0.74 | KMT2A (0.55) | SNCALMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL17356869 | 0.73 | SNCA (0.56) | SNCALMNAALDH1A1GAAMAPT | |
| SCHEMBL21752000 | 0.72 | SNCA (1.00) | SNCALMNAALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101883567-B | Therapeutic use of diaminophenothiazines | WISTA LAB LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101883567-A | Therapeutic use of diaminophenothiazines | WISTA LAB LTD | 2010-11-10 | — | — | CN | disclosed |