Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FDPS | P14324 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8567167 | 0.97 | CYP1A2 (0.50) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL3086041 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL28297813 | 0.84 | MAPT (0.39) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL22288216 | 0.84 | MAPT (0.37) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL35602 | 0.84 | — | — | |
| Phosphoric Acid SCHEMBL27798335 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL25908106 | 0.82 | CYP2C9 (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL9199503 | 0.81 | CYP2C9 (0.41) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL5874691 | 0.81 | MAPT (0.39) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL7796775 | 0.81 | MAPT (0.39) | CYP1A2CYP2C9HPGDMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101693846-B | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2012-11-21 | — | — | CN | claimed |
| CN-101693846-A | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2010-04-14 | — | — | CN | claimed |
| CN-101693846-B | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-101693846-B | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-101693846-A | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2010-04-14 | — | — | CN | disclosed |
| CN-101693846-A | Multiple combination oil soluble demulsifier | NANJING PETROCHEMICAL CO LTD | 2010-04-14 | — | — | CN | disclosed |