SCHEMBL27798380

SCHEMBL27798380

CC(C)(C)OC(=O)[C@H](CN)C(=O)ON

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33
NOS1 P29475 2/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27824269 1.00 DGAT1 (0.33) DGAT1NOS1NOS3NOS2LMNA
Hydrochloric Acid SCHEMBL27834229 0.98 DGAT1 (0.32) DGAT1NOS1NOS3NOS2
SCHEMBL27747509 0.92 NOS1 (0.36) DGAT1NOS1NOS3NOS2LMNA
SCHEMBL27382689 0.84 DGAT1 (0.33) DGAT1NOS1NOS3NOS2LMNA
SCHEMBL27937233 0.84 DGAT1 (0.33) DGAT1NOS1NOS3NOS2LMNA
SCHEMBL3693112 0.84 CA12 (0.38) DGAT1NOS1NOS3NOS2LMNA
SCHEMBL27834077 0.84 NOS1 (0.33) NOS1NOS3NOS2LMNAKMT2A
SCHEMBL3693114 0.84 CA12 (0.38) DGAT1NOS1NOS3NOS2LMNA
SCHEMBL27667693 0.84 NOS1 (0.32) NOS1NOS3NOS2
SCHEMBL6742365 0.83 KMT2A (0.38) DGAT1NOS1NOS3NOS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101932601-B Insulin derivates 诺沃-诺迪斯克有限公司 2016-08-03 CN disclosed
CN-101932601-A Insulin derivative NOVO NORDISK AS 2010-12-29 CN disclosed