SCHEMBL27798673

SCHEMBL27798673

C1=C\C=C/C2=Nc3ccccc3/C2=C\C=C/1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758940 0.92 IDO1 (0.33) IDO1
Hydroquinone SCHEMBL7243335 0.84 PLK1 (0.35)
SCHEMBL20916939 0.82 IDO1 (0.32) IDO1
SCHEMBL8140997 0.79
SCHEMBL3294467 0.74 IDO1 (0.34) IDO1
SCHEMBL29508369 0.70 IDO1 (0.37) IDO1
SCHEMBL3348606 0.69 MAOA (0.38) IDO1
SCHEMBL30804593 0.69 MAOA (0.38) IDO1
SCHEMBL28942884 0.69 IDO1 (0.32) IDO1
SCHEMBL1386767 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101687865-A A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI AVENTIS 2010-03-31 CN claimed
CN-101687865-A A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles SANOFI AVENTIS 2010-03-31 CN disclosed