SCHEMBL27799031

SCHEMBL27799031

CC(=O)Oc1nnsc1CI

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27820175 0.84 ALOX5 (0.34) ALOX5TSHR
SCHEMBL27820127 0.82 ALOX5 (0.33) ALOX5TSHR
SCHEMBL28785808 0.79 ALOX5 (0.32) ALOX5TSHR
SCHEMBL27797899 0.71 TSHR (0.30) TSHR
SCHEMBL27797610 0.61 TSHR (0.30) TSHR
SCHEMBL27797722 0.61 TSHR (0.30) TSHR
SCHEMBL9698791 0.59
SCHEMBL27797606 0.59
SCHEMBL9621256 0.58 SMN1; SMN2 (0.38) ALOX5TSHR
SCHEMBL27812081 0.57 ALOX5 (0.36) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101891709-A 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof UNIV NANKAI 2010-11-24 CN claimed
CN-101891709-B 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof UNIV NANKAI 2012-11-21 CN disclosed
CN-101891709-A 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof UNIV NANKAI 2010-11-24 CN disclosed