Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 7/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778577 | 0.83 | HDAC1 (0.47) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL21991681 | 0.80 | MAPT (0.51) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6290831 | 0.80 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10493943 | 0.79 | ATAD2 (0.53) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25804417 | 0.79 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL19992656 | 0.79 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2675622 | 0.79 | NOS3 (0.53) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2674715 | 0.78 | NOS3 (0.48) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25804489 | 0.78 | MAPT (0.56) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL14415143 | 0.78 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679397-A | Quinolone and tetrahydroquinoline having NOS inhibitory activity and related compounds | NEURAXON INC | 2010-03-24 | — | — | CN | disclosed |