Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658688 | 0.84 | CNR2 (0.39) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL27820430 | 0.84 | APP (0.37) | CNR2 | |
| SCHEMBL27820302 | 0.83 | ACACB (0.33) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL3659265 | 0.81 | CNR2 (0.40) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL27799269 | 0.80 | APP (0.37) | PDE4BPDE4APDE4CPDE4DCNR2 | |
| SCHEMBL3659745 | 0.79 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL1202625 | 0.79 | AKR1C3 (0.45) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL15111389 | 0.78 | APP (0.48) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL16488459 | 0.77 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL28789441 | 0.75 | DHFR (0.37) | PDE4BPDE4APDE4CPDE4DACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101945848-A | Tetrasubstituted benzenes | ENVIVO PHARMACEUTICALS INC | 2011-01-12 | — | — | CN | disclosed |