Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659745 | 0.92 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL3658688 | 0.86 | CNR2 (0.39) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL15494231 | 0.80 | HTR4 (0.46) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL1202625 | 0.80 | AKR1C3 (0.45) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL3657313 | 0.80 | ALDH1A1 (0.38) | HTR4PTGER4 | |
| SCHEMBL3659265 | 0.79 | CNR2 (0.40) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL15111261 | 0.78 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10301280 | 0.77 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DFFAR1 | |
| SCHEMBL27799283 | 0.77 | PDE4B (0.36) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL3655329 | 0.75 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234954-B1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS INC (US) | 2015-02-18 | — | — | EP | disclosed |