Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336588 | 0.79 | TSHR (0.48) | PPARDTSHRTP53TDP1NR1I2 | |
| SCHEMBL17635917 | 0.76 | PPARD (0.41) | PPARDTSHRTP53TDP1NR1I2 | |
| SCHEMBL7526044 | 0.75 | TSHR (0.56) | PPARDTSHRTP53TDP1NPSR1 | |
| SCHEMBL7991304 | 0.74 | TSHR (0.48) | PPARDTSHRTP53TDP1NPSR1 | |
| SCHEMBL5015252 | 0.73 | TSHR (0.53) | PPARDTSHRTP53TDP1NPSR1 | |
| SCHEMBL1396448 | 0.70 | TSHR (0.50) | PPARDTSHRTP53TDP1NPSR1 | |
| SCHEMBL6631037 | 0.70 | TSHR (0.50) | PPARDTSHRTP53TDP1NR1I2 | |
| SCHEMBL11336903 | 0.70 | TSHR (0.43) | PPARDTSHRTP53TDP1NR1I2 | |
| SCHEMBL4797316 | 0.69 | TSHR (0.48) | PPARDTSHRTP53TDP1NR1I2 | |
| SCHEMBL5357461 | 0.69 | TSHR (0.48) | PPARDTSHRTP53TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679228-A | Novel 3-phenylacrylic acid derivatives as activators of receptors of the PPAR type, method for preparing same and use thereof in cosmetic or pharmaceutical compositions | JEAN-GUY BOITEAU | 2010-03-24 | — | — | CN | disclosed |