Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19022270 | 0.88 | NR1I2 (0.44) | SMN1; SMN2TRPA1HDAC3HDAC6MAPT | |
| SCHEMBL4728410 | 0.86 | EPHX2 (0.44) | SMN1; SMN2TRPA1HDAC3HDAC6MAPT | |
| SCHEMBL4726899 | 0.86 | KDM4E (0.54) | SMN1; SMN2MAPTHPGDLMNAHTT | |
| SCHEMBL19061152 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2TRPA1MAPTHPGDNPC1 | |
| SCHEMBL22705389 | 0.85 | TRPA1 (0.41) | SMN1; SMN2TRPA1HDAC3HDAC6MAPT | |
| SCHEMBL19022128 | 0.85 | CYP1A2 (0.48) | SMN1; SMN2TRPA1MAPTGAAL3MBTL1 | |
| SCHEMBL19037775 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2TRPA1HDAC3HDAC6MAPT | |
| SCHEMBL23375439 | 0.82 | KDM4E (0.51) | SMN1; SMN2HDAC3HDAC6MAPTHPGD | |
| SCHEMBL2097862 | 0.82 | HDAC3 (0.59) | SMN1; SMN2HDAC3HDAC6MAPTNPC1 | |
| SCHEMBL19022322 | 0.81 | TRPA1 (0.36) | SMN1; SMN2TRPA1HDAC3HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939339-A | Detection of biomarkers | ATERIS TECHNOLOGIES LLC | 2011-01-05 | — | — | CN | disclosed |