Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799352 | 0.82 | SMN1; SMN2 (0.47) | KDM4EHPGDSMN1; SMN2NPC1CYP2D6 | |
| SCHEMBL20718077 | 0.77 | KDM4E (0.60) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15143918 | 0.75 | SMN1; SMN2 (0.79) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2346923 | 0.75 | GPR35 (0.47) | SMN1; SMN2NPC1RAB9AHDAC3HDAC6 | |
| SCHEMBL16259491 | 0.75 | MAPT (0.55) | SMN1; SMN2NPC1RAB9AMAPK14HDAC3 | |
| SCHEMBL4881032 | 0.75 | KDM4E (0.54) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9358296 | 0.75 | HPGD (0.71) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL73113 | 0.74 | HPGD (0.59) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14200242 | 0.74 | ALDH1A1 (0.60) | KDM4ESMN1; SMN2HDAC3HDAC6MAPT | |
| SCHEMBL9335041 | 0.73 | HPGD (0.62) | KDM4EHPGDSMN1; SMN2RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11013757-B2 | Oligonucleotides, compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2021-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11013757-B2 | Oligonucleotides, compositions and methods thereof | TLR9, RNGTT, NT5C3B | KDM4E 1751/4885HPGD 4286/4885CYP1A2 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.