Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 15/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566098 | 0.85 | EPHX2 (0.66) | EPHX2EPHX1 | |
| SCHEMBL4449239 | 0.79 | EPHX2 (0.74) | EPHX2EPHX1 | |
| SCHEMBL4016889 | 0.79 | EPHX2 (0.74) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL3213643 | 0.78 | EPHX2 (1.00) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL4013323 | 0.77 | EPHX2 (0.66) | EPHX2EPHX1 | |
| SCHEMBL4015325 | 0.73 | EPHX2 (0.69) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL13651413 | 0.72 | EPHX2 (0.74) | EPHX2EPHX1 | |
| SCHEMBL4117228 | 0.72 | EPHX2 (0.76) | EPHX2EPHX1 | |
| SCHEMBL4013218 | 0.72 | LMNA (0.63) | EPHX2EPHX1USP2LMNA | |
| SCHEMBL5146577 | 0.71 | EPHX1 (1.00) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679258-A | 4-piperidinylurea compounds as soluble epoxide hydrolase inhibitors | ARETE THERAPEUTICS INC | 2010-03-24 | — | — | CN | claimed |