Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.33 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28429659 | 0.74 | ALDH1A1 (0.37) | MEN1KMT2AKDM4EMAPK1GAA | |
| SCHEMBL27832761 | 0.70 | — | — | |
| SCHEMBL28041241 | 0.69 | MEN1 (0.41) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL27946128 | 0.67 | KDM4E (0.35) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL21616816 | 0.64 | KDM4E (0.33) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL697151 | 0.61 | AKR1C1 (0.48) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL28240863 | 0.60 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL8112531 | 0.60 | AKR1C1 (0.52) | NR4A1NR4A2NR4A3KIF11TDP1 | |
| SCHEMBL8747018 | 0.60 | SLC6A3 (0.42) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL3677596 | 0.60 | KMT2A (0.41) | MEN1KMT2AMAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110193033-A | A kind of drug and its preparation method and application for treating diabete peripheral herve pathology | 郑州工业应用技术学院 | 2019-09-03 | — | — | CN | disclosed |
| CN-205563340-U | Cassia seed extract product technology monitoring instrument | 西安源森生物科技有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-102716182-B | A kind of be used for the treatment of non-alcoholic fatty liver disease Semen Cassiae extract, preparation method and pharmacy application thereof | CHONGQING ACADEMY OF CHINESE MATERIA MEDICA (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-102716182-B | A kind of be used for the treatment of non-alcoholic fatty liver disease Semen Cassiae extract, preparation method and pharmacy application thereof | CHONGQING ACADEMY OF CHINESE MATERIA MEDICA (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-104940278-A | Application of cassia seed extract with effect of reducing blood fat in preparation of blood fat reducing medicaments and health foods | UNIV ZHEJIANG CHINESE MEDICAL | 2015-09-30 | — | — | CN | disclosed |
| CN-102716182-A | Semen cassiae extract for treating nonalcoholic fatty liver diseases as well as preparation method and application of semen cassiae extract | CHONGQING ACADEMY CHINESE MED | 2012-10-10 | — | — | CN | disclosed |
| CN-101690795-B | Tianshen vessel-freeing granules for treating cardiovascular and cerebrovascular diseases | Weihai dongbao pharmaceutical co ltd | 2012-08-08 | — | — | CN | disclosed |
| CN-101690795-A | Tianshen vessel-freeing granules for treating cardiovascular and cerebrovascular diseases | WEIHAI DONGBAO PHARMACEUTICAL | 2010-04-07 | — | — | CN | disclosed |