Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854436 | 0.74 | OPRM1 (0.40) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL20229794 | 0.73 | OPRM1 (0.73) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| Phenylacetic Acid SCHEMBL27769912 | 0.72 | KDM4E (0.60) | OPRM1OPRK1OPRD1KDM4EALDH1A1 | |
| SCHEMBL27799590 | 0.72 | ALDH1A1 (0.38) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL20229840 | 0.70 | OPRM1 (0.71) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| Phenylacetic Acid SCHEMBL27769932 | 0.69 | OPRL1 (0.77) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL20230157 | 0.69 | OPRM1 (0.78) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL853891 | 0.68 | OPRM1 (1.00) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL1272305 | 0.68 | OPRL1 (0.70) | OPRM1OPRK1OPRD1OGFRL1OPRL1 | |
| SCHEMBL20230162 | 0.67 | OPRM1 (0.74) | OPRM1OPRK1OPRD1OGFRL1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878208-B | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | PURDUE PHARMA L.P. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-101878208-A | Quinoxaline-type-piperidine compounds that replaces and uses thereof | PURDUE PHARMA LP | 2010-11-03 | — | — | CN | disclosed |