Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.83 |
| ▸ | ARG2 | P78540 | 4/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 6/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27799649 | 1.00 | GSR (0.83) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28293467 | 0.98 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27897514 | 0.94 | GSR (0.95) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28080783 | 0.91 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL18396695 | 0.91 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27492425 | 0.91 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL31541159 | 0.91 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL18396696 | 0.91 | GSR (0.91) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL7343 | 0.91 | GSR (1.00) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL15303774 | 0.91 | GSR (1.00) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115582030-A | Liquid-locking double-layer support membrane for gas separation and preparation method and application thereof | 清华大学 | 2023-01-10 | — | — | CN | claimed |
| CN-114907040-B | Method for removing carbon dioxide by grinding solid waste | 北京锦绣新技术发展有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114907040-A | Method for removing carbon dioxide by grinding solid waste | 北京锦绣新技术发展有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-114426419-B | Method for storing carbon dioxide in inorganic solid waste ceramsite mineralized concrete | 北京锦绣新技术发展有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-111804161-B | For CO2Separated amino acid ion liquid coated nano microsphere/polymer hybrid membrane | 天津工业大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114426419-A | Method for storing carbon dioxide in inorganic solid waste ceramsite mineralized concrete | 北京锦绣新技术发展有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-111804161-A | For CO2Separated amino acid ion liquid coated nano microsphere/polymer hybrid membrane | 天津工业大学 | 2020-10-23 | — | — | CN | claimed |
| CN-116832859-A | Preparation method and application of ionic liquid modified cerium oxide catalyst | 中国科学院过程工程研究所 | 2023-10-03 | — | — | CN | disclosed |
| CN-115582030-A | Liquid-locking double-layer support membrane for gas separation and preparation method and application thereof | 清华大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-114907040-B | Method for removing carbon dioxide by grinding solid waste | 北京锦绣新技术发展有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-114907040-A | Method for removing carbon dioxide by grinding solid waste | 北京锦绣新技术发展有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113912802-B | Ionic polyimine network material and preparation method thereof | 四川大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114426419-B | Method for storing carbon dioxide in inorganic solid waste ceramsite mineralized concrete | 北京锦绣新技术发展有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111804161-B | For CO2Separated amino acid ion liquid coated nano microsphere/polymer hybrid membrane | 天津工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-114426419-A | Method for storing carbon dioxide in inorganic solid waste ceramsite mineralized concrete | 北京锦绣新技术发展有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-113912802-A | Ionic type polyimine network material and preparation method thereof | 四川大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-111804161-A | For CO2Separated amino acid ion liquid coated nano microsphere/polymer hybrid membrane | 天津工业大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-102618333-A | Method for removing CO2 from blast furnace clean coal gas by using ionic liquid | UNIV LIAONING SCI & TECH | 2012-08-01 | — | — | CN | disclosed |
| CN-101700454-A | Green carbon dioxide absorbent | NANJING UNIVERSITY OF TECHNOLOGY | 2010-05-05 | — | — | CN | disclosed |