Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 1.00 |
| ▸ | ARG2 | P78540 | 4/20 | 0.59 |
| ▸ | ARG1 | P05089 | 3/20 | 0.59 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL2802757 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL8613373 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL456381 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL3359527 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1645 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL12867528 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL1000151 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL9439278 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL20362357 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 | |
| Lysine SCHEMBL15303774 | 1.00 | GSR (1.00) | GSRARG2ARG1RNPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19503 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080142-A | Polypeptide for cancer targeted therapy and corresponding drug/fluorescent dye conjugate thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094997-A | Aqueous polyurethane coatings for printing applications | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094705-A | PTH treatment for chronic kidney disease | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074077-A | Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte stimulating hormone analogs for imaging or therapy | 省卫生服务机构 | 2026-05-22 | — | — | CN | claimed |
| CN-122068110-A | Amino acid type supermolecule gel polymer electrolyte and preparation method and application thereof | 四川荣创新能动力系统有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12630588-B2 | Bicyclic peptide ligands specific for CD137 | BICYCLETX LIMITED (GB) | 2026-05-19 | — | — | US | claimed |
| CN-122070294-A | Stable vitreous material based on histidine, arginine and glutamic acid amino acids | 阵序补丁有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2026100725-A1 | ANTI-CCR8 ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF | 住友ファーマ株式会社 | 2026-05-15 | — | — | WO | claimed |
| US-20260131015-A1 | NEODEGRADER CONJUGATES | ORUM THERAPEUTICS INC (KR) | 2026-05-14 | — | — | US | claimed |
| US-20260115298-A1 | PTH Treatment Regimen Comprising Two PTH Compounds | ASCENDIS PHARMA BONE DISEASES AS (DK) | 2026-04-30 | — | — | US | claimed |
| US-4127524-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127525-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127523-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127534-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127535-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127537-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127536-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127530-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127531-A | ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |
| US-4127528-A | HEXADECAPEPTIDE, ANALGESIC | VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY | 1978-11-28 | — | — | US | claimed |