Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992542 | 0.85 | STAT3 (0.41) | STAT3PPARAPPARDCA1CA2 | |
| SCHEMBL6906905 | 0.83 | CA1 (0.50) | STAT3CA1CA2ALDH1A1ENPP1 | |
| SCHEMBL18289524 | 0.83 | CA1 (0.50) | STAT3CA1CA2ALDH1A1ENPP1 | |
| SCHEMBL8199145 | 0.80 | BCHE (0.54) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL7882874 | 0.79 | CA1 (0.44) | STAT3CA1CA2ALDH1A1ESR1 | |
| SCHEMBL21524969 | 0.79 | CA1 (0.48) | CA1CA2ALDH1A1RECQLMEN1 | |
| SCHEMBL4432596 | 0.79 | CA1 (0.49) | STAT3CA1CA2ALDH1A1ENPP1 | |
| SCHEMBL241683 | 0.79 | CA9 (0.54) | CA1CA2ALDH1A1 | |
| SCHEMBL9257428 | 0.79 | MAOB (0.49) | STAT3CA1CA2ALDH1A1TDP1 | |
| SCHEMBL4457891 | 0.78 | BLM (0.47) | PPARAALDH1A1TDP1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081827-A | A kind of preparation method and application of bilastine | 北京天弘天达医药科技股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-103788062-A | Bilastine crystal form and preparation method thereof | BEIJING BOZE DERUN MEDICAL TECHNOLOGY DEV CO LTD | 2014-05-14 | — | — | CN | claimed |
| CN-109081827-A | A kind of preparation method and application of bilastine | 北京天弘天达医药科技股份有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-109081827-A | A kind of preparation method and application of bilastine | 北京天弘天达医药科技股份有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-104402773-A | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and intermediate compounds | YUHAN CORP | 2015-03-11 | — | — | CN | disclosed |
| CN-101952273-B | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and intermediate compounds | YUHAN CORP | 2014-11-12 | — | — | CN | disclosed |
| CN-103788062-A | Bilastine crystal form and preparation method thereof | BEIJING BOZE DERUN MEDICAL TECHNOLOGY DEV CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-101952273-A | Process for the preparation of 2-methyl-2' -phenylpropionic acid derivatives and novel intermediate compounds | YUHAN CORP | 2011-01-19 | — | — | CN | disclosed |