Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16717920 | 0.87 | TACR1 (0.59) | SIGMAR1TACR1 | |
| SCHEMBL3709844 | 0.87 | KMT2A (0.50) | KMT2AMEN1TSHRSIGMAR1ACHE | |
| Hydrochloric Acid SCHEMBL5974104 | 0.85 | ACHE (0.49) | KMT2AMEN1TSHRSIGMAR1ACHE | |
| Hydrochloric Acid SCHEMBL17144149 | 0.85 | TACR1 (0.60) | SIGMAR1TACR1 | |
| Hydrochloric Acid SCHEMBL5974110 | 0.85 | ACHE (0.49) | KMT2AMEN1TSHRSIGMAR1ACHE | |
| Methyl Alcohol SCHEMBL28518805 | 0.84 | TACR1 (0.57) | SIGMAR1TACR1 | |
| SCHEMBL1622710 | 0.83 | ALDH1A1 (0.57) | KMT2AMEN1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1621693 | 0.82 | ALDH1A1 (0.56) | KMT2AMEN1 | |
| SCHEMBL1916659 | 0.80 | ACHE (0.56) | KMT2ASIGMAR1ACHETACR1BCHE | |
| Bromide SCHEMBL548941 | 0.79 | ACHE (0.54) | KMT2ASIGMAR1ACHETACR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171194-A | Pyrimidine compounds, compositions and methods of use | GENENTECH INC | 2011-08-31 | — | — | CN | disclosed |
| CN-101652367-A | Pyrimido [4, 5-D ] azepine derivatives as 5-HT 2C agonists | PFIZER LTD GB | 2010-02-17 | — | — | CN | disclosed |